• Print ISSN: 2395 - 1400, Online ISSN: 2455 - 8923

Original Article

Hematological and Morphological changes of blood cells in HIV Patients

ABSTRACT

Background: :The Human Immunodeficiency Virus infection causes the Acquired Immunodeficiency Syndrome. Besides infectious complications, several peripheral blood cell abnormalities have been reported in HIV infection, of which anaemia and Neutropenia are reportedly the most common, which may have a considerable impact on the patient’s wellbeing, and treatment.

Material and methods: Blood smears from 101 confirmed newly diagnosed HIV Positive cases were studied after taking a Written informed consent. Descriptive statistics, chi square test and contingency coefficient analysis was done using SPSS (version 16) for windows.

Results: HIV Infection affected the highly reproductive age group of 21-40 years with male predominance. Among the hematological manifestations, anemia (54.5 %) was the commonest among the patients which is predominantly Normocytic Normochromic anemia. Among the morphological changes the commonest morphological finding observed was dysplastic neutrophils.

Conclusion: There was significant statistical correlation between declining CD4 counts and Normocytic anemia, leucopenia and Thrombocytopenia. Hence all HIV Patients should be investigated for complete blood count including hematologic and morphological assessment of blood cells to reduce mortality and morbidity.

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