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Case Report

Evans syndrome and pregnancy: A case reportn


Evans syndrome is characterised by simultaneous or sequential development of autoimmune thrombocytopenia and autoimmune hemolytic anemia in the presence or absence of a known underlying cause.1,2 Autoantibodies against erythrocytes, platelets and neutrophils have been shown in Evans syndrome. Both the occurrence of isolated episodes of thrombocytopenia and hemolytic anemia and the results of in vitro studies have suggested the roles of non cross reacting autoantibodies targeted at different antigenic determinants on red cells and platelets. Both cellular and humoral immune response abnormalities have been shown in evans syndrome.

There have been a few case reports of Evans syndrome during pregnancy.3,4 we present a case of Evans syndrome during pregnancy.