• Print ISSN: 2395 - 1400, Online ISSN: 2455 - 8923

Current Issues

Pictorial Essay
Mesial Temporal sclerosis: A pictorial essay

1Post Graduate, 2Assistant Professor, 3Professor and HOD, 4Senior Resident, Department of Radiology, Kamineni Institute of Medical Sciences, Narketpally, Nalgonda, Telangana state, India.


Mesial Temporal sclerosis (MTS) is one of the commonest cause of partial complex seizures. It is the most common lesion identified histologically in adults with temporal lobe epilepsy. The etiology is controversial and it may be congenital or developmental. Mesial temporal sclerosis is characterized by neuronal loss and gliosis which contribute to its two principal findings on conventional Magentic Resonance imaging seen as hyperintensity and volume loss of the hippocampus. Conventional MR imaging is considered as a preferred imaging technique in the detection of abnormal hippocampus with a sensitivity of 85%- 98%. MR imaging findings along with EEG data strongly guide the work up of temporal lobe epilepsy patients. We present three cases of mesial temporal sclerosis. All the three cases showed unilateral hippocampal atrophy, one of the cases also showed added hippocampal hyperintensity. In this case series typical findings of MTS were seen in a paediatric age group patient (patient’s age was 18 months) which is rare.

Key words: Magnetic resonance imaging, mesial temporal sclerosis